Sudafed Sinus Pressure & Pain Tablets Sudafed Sinus Pressure & Pain Tablets contains Ibuprofen and Pseudoephedrine Hydrochloride which combine to effectively tackle the symptoms of colds and flus. They efficiently reduce temperature, unblock sinuses and reduce inflammation so you can get on with your day without distractions or discomfort. Approved by Manjit Sond – Accuracy Checking Technician on the 16/12/2021. For more information, view our medical team. Please note that results may vary.